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Connections, cognition and Alzheimer's disease / Hyman, B. T. ; Duyckaerts, C. ; Yves Christen
Titre : Connections, cognition and Alzheimer's disease Type de document : texte imprimé Auteurs : Hyman, B. T., Editeur scientifique ; Duyckaerts, C., Editeur scientifique ; Yves Christen, Editeur scientifique Editeur : Berlin : Springer Année de publication : 1997 Collection : Research and perspectives in Alzheimer's disease, ISSN 0945-6066 Importance : xiii, 193 p. Présentation : ill. (some col.) Format : 24 cm ISBN/ISSN/EAN : 978-3-540-62205-5 Langues : Anglais Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Neurosciences - Santé mentale:CerveauMots-clés : "Maladie_Alzheimer--Congrès" "Physiopathologie--Congrès" "Troubles_de_la_mémoire--Congrès" Résumé : .
The fundamental relationship between the neuropathological lesions of Alzheimer's disease and the problem of what underlies the clinical syndrome has remained unsolved since the beginning of the century. In the last decade, these questions have been revisited through systematic studies of individuals with various degrees of dementia using newer immunohistochemical techniques and quantitative approaches to neuropathological study. It is now possible to have a uniform picture of Alzheimer's disease dementia as resulting from collapse of specific neural systems, as pathological changes selectively and specifically involve structures related to memory and higher cognitive functions.This book contains the proceedings of a meeting organized by the Fondation IPSEN which brought together researchers in neuropathology, molecular biology, genetics, neuropsychology, brain imagery and clinical neurology.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1839 Connections, cognition and Alzheimer's disease [texte imprimé] / Hyman, B. T., Editeur scientifique ; Duyckaerts, C., Editeur scientifique ; Yves Christen, Editeur scientifique . - Berlin : Springer, 1997 . - xiii, 193 p. : ill. (some col.) ; 24 cm. - (Research and perspectives in Alzheimer's disease, ISSN 0945-6066) .
ISBN : 978-3-540-62205-5
Langues : Anglais
Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Neurosciences - Santé mentale:CerveauMots-clés : "Maladie_Alzheimer--Congrès" "Physiopathologie--Congrès" "Troubles_de_la_mémoire--Congrès" Résumé : .
The fundamental relationship between the neuropathological lesions of Alzheimer's disease and the problem of what underlies the clinical syndrome has remained unsolved since the beginning of the century. In the last decade, these questions have been revisited through systematic studies of individuals with various degrees of dementia using newer immunohistochemical techniques and quantitative approaches to neuropathological study. It is now possible to have a uniform picture of Alzheimer's disease dementia as resulting from collapse of specific neural systems, as pathological changes selectively and specifically involve structures related to memory and higher cognitive functions.This book contains the proceedings of a meeting organized by the Fondation IPSEN which brought together researchers in neuropathology, molecular biology, genetics, neuropsychology, brain imagery and clinical neurology.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1839 Exemplaires
Code-barres Cote Support Disponibilité 11525 08CHR Ouvrage Disponible Apolipoprotein E and Alzheimer's disease / Yves Christen
Titre : Apolipoprotein E and Alzheimer's disease Type de document : texte imprimé Auteurs : Yves Christen, Editeur scientifique ; K. H. Weisgraber, Editeur scientifique ; Allen D. Roses, Editeur scientifique Editeur : Berlin : Springer Année de publication : 1996 Collection : Research and perspectives in Alzheimer's disease, ISSN 0945-6066 Importance : xx, 188 p. Présentation : ill. (some col.) Format : 24 cm ISBN/ISSN/EAN : 978-3-540-60798-4 Note générale : Papers presented at an international meeting held in Paris on May 29, 1995 Langues : Anglais Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Neurosciences - Santé mentale:CerveauMots-clés : "Maladie_Alzheimer--Congrès" "Maladie_Alzheimer--Étiologie--Congrès" "Apolipoproteine_E" Résumé : .
There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new field, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1840 Apolipoprotein E and Alzheimer's disease [texte imprimé] / Yves Christen, Editeur scientifique ; K. H. Weisgraber, Editeur scientifique ; Allen D. Roses, Editeur scientifique . - Berlin : Springer, 1996 . - xx, 188 p. : ill. (some col.) ; 24 cm. - (Research and perspectives in Alzheimer's disease, ISSN 0945-6066) .
ISBN : 978-3-540-60798-4
Papers presented at an international meeting held in Paris on May 29, 1995
Langues : Anglais
Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Neurosciences - Santé mentale:CerveauMots-clés : "Maladie_Alzheimer--Congrès" "Maladie_Alzheimer--Étiologie--Congrès" "Apolipoproteine_E" Résumé : .
There is now considerable genetic evidence that the type 4 allele of the apolipoprotein E gene is a major susceptibility factor associated with late-onset Alzheimer's disease, the common form of the disease defined as starting after sixty years of age. The role of apolipoprotein E in normal brain metabolism and in the pathogenesis of Alzheimer's disease are new and exciting avenues of research. This book, written by the most outstanding scientists in this new field, is the first presentation of results concerning the implications of apolipoprotein E on the genetics, cell biology, neuropathology, biochemistry, and therapeutic management of Alzheimer's disease.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1840 Exemplaires
Code-barres Cote Support Disponibilité 11526 08CHR Ouvrage Disponible Presenilins and Alzheimer's disease / Yves Christen ; Younkin, S. G. ; Tanzi, Rudolph E.
Titre : Presenilins and Alzheimer's disease Type de document : texte imprimé Auteurs : Yves Christen, Editeur scientifique ; Younkin, S. G., Editeur scientifique ; Tanzi, Rudolph E., Editeur scientifique Editeur : Berlin : Springer Année de publication : 1998 Collection : Research and perspectives in Alzheimer's disease, ISSN 0945-6066 Importance : xv, 100 p. Présentation : ill. (some col.) Format : 24 cm ISBN/ISSN/EAN : 978-3-540-63997-8 Langues : Anglais Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Maladies:Génétique et ses applications:Maladies génétiques
Neurosciences - Santé mentale:CerveauMots-clés : "MALADIE_ALZHEIMER--GENETIQUE" "PROTEINES_EMBRANAIRES--PHYSIOLOGIE" "Maladie_Alzheimer--Aspect_génétique" "Maladie_Alzheimer--Aspect_moléculaire" "Protéines_membranaires--physiologie" Résumé : .
The discovery in 1995 that defects in the novel presenilin genes harbor defects which cause up to half of all cases of early onset familial Alzheimer's disease cases has rapidly led to the creation of a new and exciting sub-field in Alzheimer's disease research. This has clearly been evidenced by the fact that over 250 papers have now been published regarding the presenilins since their identification in 1995. One of the earliest findings regarding the role of the presenilins in Alzheimer's disease was the discovery that like familial Alzheimer's disease mutations in the amyloid ß protein precursor gene, those in the presenilins lead to dramatically increased production of ß-amyloid in the brains of AD patients. Additionally, the presenilins appear to play roles in programmed cell death (apoptosis) and in CNS development. The provocative chapters in this book written by some of the most highly respected experts in the area of Alzheimer's disease research present some of the latest information concerning the biological function of the presenilins and how defects in these genes cause Alzheimer's disease. The knowledge contained in this volume should help to accelerate ongoing attempts to develop novel treatments for Alzheimer's disease and related disorders.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1841 Presenilins and Alzheimer's disease [texte imprimé] / Yves Christen, Editeur scientifique ; Younkin, S. G., Editeur scientifique ; Tanzi, Rudolph E., Editeur scientifique . - Berlin : Springer, 1998 . - xv, 100 p. : ill. (some col.) ; 24 cm. - (Research and perspectives in Alzheimer's disease, ISSN 0945-6066) .
ISBN : 978-3-540-63997-8
Langues : Anglais
Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Maladies:Génétique et ses applications:Maladies génétiques
Neurosciences - Santé mentale:CerveauMots-clés : "MALADIE_ALZHEIMER--GENETIQUE" "PROTEINES_EMBRANAIRES--PHYSIOLOGIE" "Maladie_Alzheimer--Aspect_génétique" "Maladie_Alzheimer--Aspect_moléculaire" "Protéines_membranaires--physiologie" Résumé : .
The discovery in 1995 that defects in the novel presenilin genes harbor defects which cause up to half of all cases of early onset familial Alzheimer's disease cases has rapidly led to the creation of a new and exciting sub-field in Alzheimer's disease research. This has clearly been evidenced by the fact that over 250 papers have now been published regarding the presenilins since their identification in 1995. One of the earliest findings regarding the role of the presenilins in Alzheimer's disease was the discovery that like familial Alzheimer's disease mutations in the amyloid ß protein precursor gene, those in the presenilins lead to dramatically increased production of ß-amyloid in the brains of AD patients. Additionally, the presenilins appear to play roles in programmed cell death (apoptosis) and in CNS development. The provocative chapters in this book written by some of the most highly respected experts in the area of Alzheimer's disease research present some of the latest information concerning the biological function of the presenilins and how defects in these genes cause Alzheimer's disease. The knowledge contained in this volume should help to accelerate ongoing attempts to develop novel treatments for Alzheimer's disease and related disorders.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1841 Exemplaires
Code-barres Cote Support Disponibilité 11524 08CHR Ouvrage Disponible Ethical issues of molecular genetics in psychiatry / Yves Christen
Titre : Ethical issues of molecular genetics in psychiatry Type de document : texte imprimé Auteurs : Yves Christen, Editeur scientifique ; Srám, R. J., Editeur scientifique ; Fondation IPSEN pour la recherche thérapeutique. ; World Health Organization. ; Victor Bulyzhenkov, Editeur scientifique ; Leonid Prilipko, Editeur scientifique Editeur : Berlin : Springer Année de publication : 1991 Importance : x, 177 p. Présentation : ill. Format : 25 cm ISBN/ISSN/EAN : 978-0-387-53675-0 Note générale : Based on an international conference held in Brno, Czechoslovakia, June 11-12, 1990, organized by the WHO Division of Mental Health, in collaboration with the IPSEN Foundation Langues : Anglais Catégories : Enseignements - Communications:Actes de colloques, Congrès ...
Maladies:Génétique et ses applications:Maladies génétiques
Neurosciences - Santé mentale:CerveauMots-clés : "Maladies_mentales--Aspect_génétique--Aspect_moral--Congrès" "Éthique_médicale--Congrès" "Trouble_mental--génétique--congrès" "Génétique_médicale--Congrès" "Génétique_moléculaire--Congrès" Résumé : .
The dramatic developments in molecular genetics have brought up new ethical challenges. This book presents the discus- sions which emerged from a joint meeting of the Foundation IPSEN and the WHO in Brno, close to the monastery where Gregor Mendel founded the science of genetics, where a number of molecular geneticists, psychiatrists, churchmen, and legal professionals metto consider just these topics.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1842 Ethical issues of molecular genetics in psychiatry [texte imprimé] / Yves Christen, Editeur scientifique ; Srám, R. J., Editeur scientifique ; Fondation IPSEN pour la recherche thérapeutique. ; World Health Organization. ; Victor Bulyzhenkov, Editeur scientifique ; Leonid Prilipko, Editeur scientifique . - Berlin : Springer, 1991 . - x, 177 p. : ill. ; 25 cm.
ISBN : 978-0-387-53675-0
Based on an international conference held in Brno, Czechoslovakia, June 11-12, 1990, organized by the WHO Division of Mental Health, in collaboration with the IPSEN Foundation
Langues : Anglais
Catégories : Enseignements - Communications:Actes de colloques, Congrès ...
Maladies:Génétique et ses applications:Maladies génétiques
Neurosciences - Santé mentale:CerveauMots-clés : "Maladies_mentales--Aspect_génétique--Aspect_moral--Congrès" "Éthique_médicale--Congrès" "Trouble_mental--génétique--congrès" "Génétique_médicale--Congrès" "Génétique_moléculaire--Congrès" Résumé : .
The dramatic developments in molecular genetics have brought up new ethical challenges. This book presents the discus- sions which emerged from a joint meeting of the Foundation IPSEN and the WHO in Brno, close to the monastery where Gregor Mendel founded the science of genetics, where a number of molecular geneticists, psychiatrists, churchmen, and legal professionals metto consider just these topics.Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=1842 Exemplaires
Code-barres Cote Support Disponibilité 11604 09CHR Ouvrage Disponible Genotype - proteotype - phenotype relationships in neurodegenerative diseases / Yves Christen
Titre : Genotype - proteotype - phenotype relationships in neurodegenerative diseases Type de document : texte imprimé Auteurs : Yves Christen, Editeur scientifique ; Jeffrey L. Cummings, Editeur scientifique ; John Hardy, Editeur scientifique ; Michel Poncet, Editeur scientifique Editeur : Berlin : Springer Année de publication : 2005 Collection : Research and perspectives in Alzheimer's disease, ISSN 0945-6066 Importance : XIII-166 p. Présentation : ill. Format : 24 cm ISBN/ISSN/EAN : 978-3-540-24835-4 Langues : Anglais Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Maladies:Génétique et ses applications:Génome
Neurosciences - Santé mentale:CerveauMots-clés : "Système_nerveux--Dégénérescence--Aspect_moléculaire" "Maladies_neurodégénératives--congrès" "Génotype--Congrès" "Phénotype--Congrès" "Système_nerveux--Dégénérescence--Congrès" Résumé : .
Protein misfolding and other abnormalities of protein metabolism are increasingly recognized as central mechanisms in the pathophysiology of neurodegenerative disorders. Amyloid beta protein disturbances in Alzheimer's disease, tau and ubiquitin protein abnormalities in frontotemporal dementias, proteasome and alphasynuclein disorders in Parkison's disease and dementia with Lewy bodies comprise central elements in these common neurodegenerative diseases. Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegeberative diseases.Note de contenu : Bibliogr. à la fin des chapitres. Index Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=2917 Genotype - proteotype - phenotype relationships in neurodegenerative diseases [texte imprimé] / Yves Christen, Editeur scientifique ; Jeffrey L. Cummings, Editeur scientifique ; John Hardy, Editeur scientifique ; Michel Poncet, Editeur scientifique . - Berlin : Springer, 2005 . - XIII-166 p. : ill. ; 24 cm. - (Research and perspectives in Alzheimer's disease, ISSN 0945-6066) .
ISBN : 978-3-540-24835-4
Langues : Anglais
Catégories : Maladies:Etude des maladies:Maladie d'Alzheimer
Maladies:Génétique et ses applications:Génome
Neurosciences - Santé mentale:CerveauMots-clés : "Système_nerveux--Dégénérescence--Aspect_moléculaire" "Maladies_neurodégénératives--congrès" "Génotype--Congrès" "Phénotype--Congrès" "Système_nerveux--Dégénérescence--Congrès" Résumé : .
Protein misfolding and other abnormalities of protein metabolism are increasingly recognized as central mechanisms in the pathophysiology of neurodegenerative disorders. Amyloid beta protein disturbances in Alzheimer's disease, tau and ubiquitin protein abnormalities in frontotemporal dementias, proteasome and alphasynuclein disorders in Parkison's disease and dementia with Lewy bodies comprise central elements in these common neurodegenerative diseases. Improved understanding of role of protein dysmetabolism in neurodegeneration promises to improve diagnoses, facilitate the development of biological markers relevant to disease pathophysiology, and provide tractable therapeutic targets. This Fondation IPSEN conference summary provides an update on the latest advances of the role of protein misfolding in the pathophysiology of neurodegeberative diseases.Note de contenu : Bibliogr. à la fin des chapitres. Index Permalink : http://www.2em.org/pmb/opac_css/index.php?lvl=notice_display&id=2917 Exemplaires
Code-barres Cote Support Disponibilité 11523 08CHR Ouvrage Disponible Neurobiology of Human Values / Yves Christen
PermalinkAlzheimer : 100 years and beyond / Yves Christen
PermalinkIntracellular traffic and neurodegenerative disorders / Yves Christen
PermalinkMemories: molecules and circuits / Yves Christen
PermalinkRetrotransposition, diversity, and the brain / Yves Christen
PermalinkNeurobiology of "Umwelt" / Yves Christen
PermalinkMacro roles for microRNAs in the life and death of neurons / Yves Christen
PermalinkNew frontiers in social neuroscience / Fondation IPSEN pour la recherche thérapeutique.
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